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Biography

Professional biography

PhD in Biostatistics, Harvard University.
M.Sc. in Biostatistics, Harvard University.
M.Stat. in Statistics, Indian Statistical Institute.
B.Stat. in Statistics, Indian Statistical Institute.

Postdoctoral Research Associate, University College London.

Research interests

The main area of my research is Statistical Genetics. My research interests on human genetics can be split into two major avenues:  

  • Population genetics of admixed human populations, such as Latin America and South Asia.
  • The genetics of human appearance and normal physical variation, such as facial morphology or pigmentation. I study these through genome-wide association studies (GWAS), and build prediction models for forensic reconstruction.

In these contexts, I study signals of natural selection and evolution, such as the evolution of light skin in Eurasia. 

I’m looking into developing computational methods to address big data problems in high-dimensional genetic and phenotypic data.

A key focus of my work is increasing the diversity of genetics research, by looking at other diverse human populations outside of the Eurocentric emphasis in most GWAS studies

Impact and engagement

I have a keen interest in public engagement on statistics and statistical genetics, in particular about their misuse and misunderstandings. 

  • I am the Statistics consultant for the BBC radio program ‘More or Less’.
  • I present Masterclasses on Statistics at the Royal Institution.
  • I have written popular science articles at The Conversation and on OpenLearn.
  • My forensics research have been featured on ‘DNA+’, a BBC documentary exploring modern genetics.

Projects

Talking Genetics with Art and Craft

The proposed project is a collaboration between the OU’s Genetics Research Awareness via Community Engagement (GRACE) project and Breaking Down Barriers (BDB) https://breaking-down-barriers.org.uk/ . Using art, craft and other hands-on activities to generate conversations about genetics, the project aims to foster greater awareness of, diversity in, and equitable access to genetics research and healthcare.

RAMP Outreach Innovation Award

Payment of Graphic Artist

Publications

Journal Article

Death toll among the Bangladeshi refugees of the 1971 war (2025)

Health Economic Consequences Associated With COVID-19–Related Delay in Melanoma Diagnosis in Europe (2024)

PITX2 expression and Neanderthal introgression in HS3ST3A1 contribute to variation in tooth dimensions in modern humans (2024)

Neanderthal introgression in SCN9A impacts mechanical pain sensitivity (2023)

Combined genome-wide association study of 136 quantitative ear morphology traits in multiple populations reveal 8 novel loci (2023)

Automatic landmarking identifies new loci associated with face morphology and implicates Neanderthal introgression in human nasal shape (2023)

Genome-wide association studies identify DNA variants influencing eyebrow thickness variation in Europeans and across continental populations (2023)

Dental size variation in admixed Latin Americans: Effects of age, sex and genomic ancestry (2023)

Sequential changes in cellular properties accompanying amniote somite formation (2023)

Sodium-calcium exchanger-3 regulates pain "wind-up": From human psychophysics to spinal mechanisms (2022)

Clotting factor genes are associated with preeclampsia in high-altitude pregnant women in the Peruvian Andes (2022)

A genome-wide scan on individual typology angle found variants at SLC24A2 associated with skin color variation in Chinese populations (2022)

Disentangling Signatures of Selection Before and After European Colonization in Latin Americans (2022)

Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits - the Hispanic/Latino Anthropometry Consortium (2022)

NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism (2021)

Prediction of eye, hair and skin colour in Latin Americans (2021)

The impact of socioeconomic and phenotypic traits on self-perception of ethnicity in Latin America (2021)

A GWAS in Latin Americans identifies novel face shape loci, implicating VPS13B and a Denisovan introgressed region in facial variation (2021)

Factors associated with hypertension in Pakistan: A systematic review and meta-analysis (2021)

A GWAS identifies novel gene associations with facial skin wrinkling and mole count in Latin‐Americans (2021)

Novel genetic loci affecting facial shape variation in humans (2019)

Modeling Population Structure Under Hierarchical Dirichlet Processes (2019)

Genetic components of human pain sensitivity: a protocol for a genome-wide association study of experimental pain in healthy volunteers (2019)

Variation in dental morphology and inference of continental ancestry in admixed Latin Americans (2019)

Obesity, genomic ancestry, and socioeconomic variables in Latin American mestizos (2019)

A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia (2019)

A geometric morphometric approach to the study of variation of shovel-shaped incisors (2019)

Genome-wide association studies and CRISPR/Cas9-mediated gene editing identify regulatory variants influencing eyebrow thickness in humans (2018)

Latin Americans show wide-spread Converso ancestry and imprint of local Native ancestry on physical appearance (2018)

Developmental pathways inferred from modularity, morphological integration and fluctuating asymmetry patterns in the human face (2018)

Socioeconomic Status Is Not Related with Facial Fluctuating Asymmetry: Evidence from Latin-American Populations (2017)

A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features (2016)

A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation (2016)

A genome-wide association study identifies multiple loci for variation in human ear morphology (2015)

Admixture in Latin America: Geographic Structure, Phenotypic Diversity and Self-Perception of Ancestry Based on 7,342 Individuals (2014)

Presentation / Conference

Assessment and feedback on the introduction of group work on a level 1 statistics module (M140) (2024)

Report

Exploring The Diversity Of Our Skin (2022)